LoRaWAN defines a specific set of data rates, but the LoRa chip or PHY is capable of more options. The SX1272 supports data rates from 0.3 to 37.5kbps and the SX1276 0.018 to 37.5kbps. Later generation parts also offer support for Spreading Factor 5, increasing further the throughput.

The LoRa modem is capable of co-channel GMSK rejection of up to 19.5 dB or stated differently, it can receive signals 19.5dB below an interfering signal or the noise floor. This immunity to interference permits the simple coexistence of LoRa modulated systems either in bands of heavy spectral usage or in hybrid communication networks that use LoRa to extend range when legacy modulation schemes fail. The addition of the Long Interleaver in newer products increases the resistance to burst interferers during reception, even if their power exceeds 19.5dB above the co-channel resistance specification.